| Haloperidol | 0.5 to 1mg q4h PO/IM/ IV prn | Best evidence in treating delirium, can cause akathisia as high potency, Needs telemetry if using IV |
| Olanzapine | 2.5mg QHS or BID and 1.25 mg q6hrs PRN | Can be deliriogenic. Good for sedation |
| Quetiapine | 12.5mg to 25 mg QHS PO plus 12.5mg q6h PRN | Sedating, anticholinergic. Worse for QTc. Best for Parkinson’s. LBD |
| Risperidone | 0.5 mg BID and 0.25mg q8hrs prn | High potency, can cause akathisia |
| Valproic Acid | 250mg BID, can increase to 500mg BID if well tolerated | Check VPA level 5th day (trough), Check LFTs, NH3 |
| Gabapentin | 100-300mg TID, scheduled or PRN | Check renal function before starting. Good for anxiety as well |
| Trazodone | 12.5mg BID, titrating up to 25mg BID to TID, standing or PRN for sedation | Use only for sedation. Can be deliriogenic |
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